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1

Lipase Action on Some Non-Triglyceride Substrates

Imre Vallikivi, Ulo Lille, Aivar Lookene, Andrus Metsala, Peeter Sikk, Vello Tougu, Heiki Vija, Ly Villo, Omar Parve

Journal:

Year:

2004

File:

PDF, 56 KB

2004

2

Single-step enzymatic conversion of peptide amides to esters

Helle Meos, Mati Haga, Vello Tõugu

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 220 KB

english, 1995

3

Lipase-catalysed enantioselective hydrolysis: Interpretation of the kinetic results in terms of frontier orbital localisation

Omar Parve, Imre Vallikivi, Andrus Metsala, Ülo Lille, Vello Tõugu, Peeter Sikk, Tuuli Käämbre, Heiki Vija, Tõnis Pehk

Journal:

Year:

1997

Language:

english

File:

PDF, 619 KB

english, 1997

4

Single-step synthesis of kyotorphin in frozen solutions by chymotrypsin

Helle Meos, Vello Tõugu, Mati Haga, Aavo Aaviksaar, Matthias Schuster, Hans-Dieter Jakubke

Journal:

Tetrahedron: Asymmetry

Year:

1993

Language:

english

File:

PDF, 266 KB

english, 1993

5

Lipase-catalysed esterification in supercritical carbon dioxide and in hexane

Heiki Vija, Artur Telling, Vello Tõugu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 220 KB

english, 1997

6

Lipase-catalysed enantioselective hydrolysis of bicyclo[3.2.0]heptanol esters in supercritical carbon dioxide

Omar Parve, Imre Vallikivi, Lilja Lahe, Andrus Metsala, Ülo Lille, Vello Tõugu, Heiki Vija, Tõnis Pehk

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 497 KB

english, 1997

7

Interference of low-molecular substances with the thioflavin-T fluorescence assay of amyloid fibrils

Andra Noormägi, Kateryna Primar, Vello Tõugu, Peep Palumaa

Journal:

Journal of Peptide Science

Year:

2012

Language:

english

File:

PDF, 336 KB

english, 2012

8

Binding of zinc(II) and copper(II) to the full-length Alzheimer’s amyloid-β peptide

Vello Tõugu, Ann Karafin, Peep Palumaa

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 323 KB

english, 2008

9

Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-β (1–42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators

Vello Tõugu, Ann Karafin, Kairit Zovo, Roger S. Chung, Claire Howells, Adrian K. West, Peep Palumaa

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 1020 KB

english, 2009

10

Aminolysis of acyl-chymotrypsins by amino acids. Kinetic appearance of concentration effect in peptide yield enhancement by freezing

Vello Tõugu, Peeter Talts, Helle Meos, Mat Haga, Aavo Aaviksaar

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1995

Language:

english

File:

PDF, 412 KB

english, 1995

11

NMR monitoring of lipase-catalyzed reactions of prostaglandins: preliminary estimation of reaction velocities

Imre Vallikivi, Ivar Järving, Tõnis Pehk, Nigulas Samel, Vello Tõugu, Omar Parve

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2004

Language:

english

File:

PDF, 129 KB

english, 2004

12

The modelling and kinetic investigation of the lipase-catalysed acetylation of stereoisomeric prostaglandins

Imre Vallikivi, Linda Fransson, Karl Hult, Ivar Järving, Tõnis Pehk, Nigulas Samel, Vello Tõugu, Ly Villo, Omar Parve

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2005

Language:

english

File:

PDF, 315 KB

english, 2005

13

Comparison of salt effects on the reactions of acetylcholinesterase with cationic and anionic inhibitors

Vello Tõugu, Tõnu Kesvatera

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2001

Language:

english

File:

PDF, 184 KB

english, 2001

14

Role of ionic interactions in cholinesterase catalysis

Vello Tõugu, Tõnu Kesvatera

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1996

Language:

english

File:

PDF, 1.78 MB

english, 1996

15

Hydrolysis of emulsified mixtures of triacylglycerols by pancreatic lipase

Tuuli Käämbre, Vello Tõugu, Peeter Käämbre, Heiki Vija, Peeter Sikk

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1999

Language:

english

File:

PDF, 242 KB

english, 1999

16

Lipase action on some non-triglyceride substrates

Imre Vallikivi, Ülo Lille, Aivar Lookene, Andrus Metsala, Peeter Sikk, Vello Tõugu, Heiki Vija, Ly Villo, Omar Parve

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2003

Language:

english

File:

PDF, 342 KB

english, 2003

17

Electrostatic effects in trypsin reactions : Influence of salts

Vello TÕUGU, Toomas TIIVEL, Peeter TALTS, Virginius ŠIKŠNIS, Svetlana POYARKOVA, Tõnu KESVATERA, Aavo AAVIKSAAR

Journal:

Year:

1994

Language:

english

File:

PDF, 697 KB

english, 1994

18

Peptide synthesis by chymotrypsin in frozen solutions: Free amino acids as nucleophiles

Vello Tõugu, Helle Meos, Mati Haga, Aavo Aaviksaar, Hans-Dieter Jakubke

Journal:

Year:

1993

Language:

english

File:

PDF, 359 KB

english, 1993

19

Coordination of zinc ions to the key proteins of neurodegenerative diseases: Aβ, APP, α-synuclein and PrP

Vello Tõugu, Peep Palumaa

Journal:

Coordination Chemistry Reviews

Year:

2012

Language:

english

File:

PDF, 354 KB

english, 2012

20

Interactions of Zn(ii) and Cu(ii) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity

Tõugu, Vello, Tiiman, Ann, Palumaa, Peep

Journal:

Year:

2011

Language:

english

File:

PDF, 1.85 MB

english, 2011

21

The missing link in the amyloid cascade of Alzheimer’s disease – Metal ions

Tiiman, Ann, Palumaa, Peep, Tõugu, Vello

Journal:

Neurochemistry International

Year:

2013

Language:

english

File:

PDF, 625 KB

english, 2013

22

Effect of agitation on the peptide fibrillization: Alzheimer's amyloid- β peptide 1-42 but not amylin and insulin fibrils can grow under quiescent conditions

Tiiman, Ann, Noormägi, Andra, Friedemann, Merlin, Krishtal, Jekaterina, Palumaa, Peep, Tõugu, Vello

Journal:

Journal of Peptide Science

Year:

2013

Language:

english

File:

PDF, 791 KB

english, 2013

23

Redox and Metal Ion Binding Properties of Human Insulin-like Growth Factor 1 Determined by Electrospray Ionization Mass Spectrometry

Smirnova, Julia, Muhhina, Jekaterina, Tõugu, Vello, Palumaa, Peep

Journal:

Year:

2012

Language:

english

File:

PDF, 615 KB

english, 2012

24

Calbindin D 9k : A Protein Optimized for Calcium Binding at Neutral pH †

Kesvatera, Tõnu, Jönsson, Bo, Telling, Artur, Tõugu, Vello, Vija, Heiki, Thulin, Eva, Linse, Sara

Journal:

Year:

2001

Language:

english

File:

PDF, 88 KB

english, 2001

25

Metallothionein 2A affects the cell respiration by suppressing the expression of mitochondrial protein cytochrome c oxidase subunit II

Bragina, Olga, Gurjanova, Karina, Krishtal, Jekaterina, Kulp, Maria, Karro, Niina, Tõugu, Vello, Palumaa, Peep

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

26

AIP Conference Proceedings [AIP Publishing LLC INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2014 (ICCMSE 2014) - Athens, Greece (4–7 April 2014)] - Copper(II) ions and the Alzheimer's amyloid-β peptide: Affinity and stoichiometry of binding

Tõugu, Vello, Friedemann, Merlin, Tiiman, Ann, Palumaa, Peep

Year:

2014

Language:

english

File:

PDF, 259 KB

english, 2014

27

In vitro fibrillization of Alzheimer’s amyloid-β peptide (1-42)

Tiiman, Ann, Krishtal, Jekaterina, Palumaa, Peep, Tõugu, Vello

Journal:

Year:

2015

Language:

english

File:

PDF, 4.27 MB

english, 2015

28

Insulin Fibrillization at Acidic and Physiological pH Values is Controlled by Different Molecular Mechanisms

Noormägi, Andra, Valmsen, Karin, Tõugu, Vello, Palumaa, Peep

Journal:

The Protein Journal

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

29

Zn(II) ions co-secreted with insulin suppress inherent amyloidogenic properties of monomeric insulin

Noormägi, Andra, Gavrilova, Julia, Smirnova, Julia, Tõugu, Vello, Palumaa, Peep

Journal:

Biochemical Journal

Year:

2010

Language:

english

File:

PDF, 636 KB

english, 2010

30

Toxicity of amyloid beta 1-40 and 1-42 on SH-SY5Y cell line

Krishtal, Jekaterina, Bragina, Olga, Metsla, Kristel, Palumaa, Peep, Tõugu, Vello

Journal:

Year:

2015

Language:

english

File:

PDF, 580 KB

english, 2015

31

Effect of methionine-35 oxidation on the aggregation of amyloid-β peptide

Friedemann, Merlin, Helk, Eneken, Tiiman, Ann, Zovo, Kairit, Palumaa, Peep, Tõugu, Vello

Journal:

Biochemistry and Biophysics Reports

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

32

Oxidation of Methionine-35 in Alzheimer’s amyloid-beta peptide and the aggregation of the oxidized peptide

Friedemann, Merlin, Helk, Eneken, Tiiman, Ann, Zovo, Kairit, Palumaa, Peep, Tõugu, Vello

Journal:

Year:

2015

Language:

english

File:

PDF, 580 KB

english, 2015

33

Copper(I)-binding properties of de-coppering drugs for the treatment of Wilson disease. α-Lipoic acid as a potential anti-copper agent

Smirnova, Julia, Kabin, Ekaterina, Järving, Ivar, Bragina, Olga, Tõugu, Vello, Plitz, Thomas, Palumaa, Peep

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.07 MB

english, 2018

34

Redox properties of Cys 2 His 2 and Cys 4 zinc fingers determined by electrospray ionization mass spectrometry

Smirnova, Julia, Kabin, Ekaterina, Tõugu, Vello, Palumaa, Peep

Journal:

Year:

2018

Language:

english

File:

PDF, 517 KB

english, 2018

35

In situ fibrillizing amyloid-beta 1-42 induces neurite degeneration and apoptosis of differentiated SH-SY5Y cells

Krishtal, Jekaterina, Bragina, Olga, Metsla, Kristel, Palumaa, Peep, Tõugu, Vello, Ginsberg, Stephen D

Journal:

Year:

2017

Language:

english

File:

PDF, 8.07 MB

english, 2017

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